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Urine Specimen Drug Abuse Test Kit Detection Of Desmethylcitalopram

Urine Specimen Drug Abuse Test Kit Detection Of Desmethylcitalopram

  • Product
    Urine Specimen Drug Abuse Test Kit Detection Of Desmethylcitalopram
  • Cat. No.
    DCIT-102
  • Principle
    Chromatographic Immunoassay
  • Format
    Cassette
  • Specimen
    Urine
  • Certificate
    CE
  • Reading Time
    5 Minutes
  • Pack
    25/40/50T
  • Sensitivity
    93.3%
  • Specificity
    95.5%
  • Accuracy
    94.8%
  • Cut-Off
    500 Ng/mL
  • Place of Origin
    -
  • Brand Name
    Citest
  • Certification
    CE
  • Model Number
    DCIT-102
  • Minimum Order Quantity
    N/A
  • Price
    negotiation
  • Packaging Details
    50T
  • Supply Ability
    10 M tests/month

Urine Specimen Drug Abuse Test Kit Detection Of Desmethylcitalopram

Citalopram (CIT) Rapid Test Cassette (Urine), Drug Abuse Test Kit. Detection Of Desmethylcitalopram

 

Product Name: CIT Rapid Test Cassette (Urine), Drug Abuse Test Kit. Detection Of Desmethylcitalopram
Brand: Citest
Format: Cassette
Certificate: CE
Pack: 25T/40T/50T
Shelf Life: 2 Years
Specificity: 95.50%
Cut-Off: 500 Ng/mL
CAT NO.: DCIT-102
Principle: Chromatographic Immunoassay
Specimen: Urine
Reading Time: 5 Minutes
Storage Temperature: 2-30°C
Sensitivity: 93.30%
Accuracy: 94.80%
PRODUCT FEATURES: Multiple Formats Available

 

CIT Rapid Test Cassette (Urine), Drug Abuse Test Kit. detection of Desmethylcitalopram

 

A rapid test for the qualitative detection of Desmethylcitalopram in human urine.For professional in vitro diagnostic use only
 
Application
 
detection of Desmethylcitalopram in urine at a cut-off concentration of 500ng/ml. This test will detect other related compounds.
This assay provides only a qualitative, preliminary analytical test result. A more specific alternate chemical method must be used in order to obtain a confirmed analytical result.Gas chromatography/mass spectrometry (GC/MS) is the preferred confirmatory method.
Clinical consideratio an professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are used.
 
PRINCIPLE
 
The CIT Rapid Test Cassette (Urine) is an immunoassay based on the principle of competitive binding. Drugs which may be present in the urine specimen compete against the drug conjugate for binding sites on the antibody. During testing, a urine specimen migrates upward by capillary action. Desmethylcitalopram, if present in the urine specimen below the cut-off level, will not saturate the binding sites of the antibody in the test. The antibody coated particles will then be captured by immobilized Citalopram-protein conjugate and a visible colored line will show up in the test line region. The colored line will not form in the test line region if the Desmethylcitalopram level exceeds the cut-off level, because it will saturate all the binding sites of anti-citalopram antibody.
 
A drug-positive urine specimen will not generate a colored line in the test line region because of drug competition, while a drug-negative urine specimen or a specimen containing a drug concentration less than the cut-off will generate a line in the test line region. To serve as a procedural control, a colored line will always appear at the control line region indicating that proper volume of specimen has been added and membrane wicking has occurred.
 
PRECAUTIONS

 

  • For professional in vitro diagnostic use only.
  • Do not use after the expiration date.
  • The test should remain in the sealed pouch until use.
  • All specimens should be considered potentially hazardous and handled in the same manner as an infectious agent.
  • The used test should be discarded according to local regulations.
DIRECTIONS FOR USE
 
Allow the test, urine specimen, and/or controls to reach room temperature (15-30C)
prior to testing.
 
1. Bring the pouch to room temperature before opening it. Remove the test cassette from the sealed pouch and use it within one hour
2. Place the cassette on a clean and level surface. Hold the dropper vertically and transfer 3 full drops of urine (approx. 120ul) to the specimen well(S) of the cassette, and then start the timer. Avoid trapping air bubbles in the specimen well(S).
3. Wait for the colored line(s) to appear. Read results at 5 minutes. Do not interpret the result after 10 minutes.
 
Urine Specimen Drug Abuse Test Kit Detection Of Desmethylcitalopram 0
 
SUMMARY
 
Citalopram, an antidepressant of the selective serotonin reuptake inhibitor (SSRI) type, is only available as a racemic drug. Its metabolism occurs, partially, by N-demethylation to demethylcitalopram (DCIT) and didemethylcitalopram (DDCIT), but also by deamination to a propionic acid derivative (CIT-PROP) and by N-oxidation to CIT-N-oxide (NO-CIT) [1] . CIT has equal affinity for 5-HTT and dopamine transporters [2] . Studies have shown that compared with healthy subjects, the binding potential of thalamus and brainstem binding area in patients with depression who take 20-60 mg citalopram every day is reduced by 50% .
 
It is supplied as the free base in 20 mg tablets oral administration; daily oral dose for adults usually range from 20-60 mg. The common adverse reactions were nausea, dry mouth and drowsiness. The rare adverse reactions were agitation, income and anxiety. The oral bioavailability of citalopram is about 80%. 15% of citalopram is excreted by kidney, and 12%-23% of citalopram in daily dose is excreted in original form from urine.